Simulation & emulators
Boycott Advance
GameBoy Advance emuator for Mac
BSNES
Super Nintendo emulator that doesn't let you save games
Dapplegrey
A graphic interface for the DOSBox emulator
DeSmuME
A Nintendo DS emulator
Dolphin
Play Wii games on your Mac
DOSBox
MS-DOS through this emulator
Fuse
Spectrum emulator for Mac
Generator
An emulator for this 16-bit Sega console
MAME OS X
A Mac version of the classic arcade game emulator
NoxPlayer
One of the most powerful emulators for Android
PCSX
A Playstation emulator for Mac
Poolstars
Play billiards against players from all around the world
Road Fighter Remake
Unofficial, the classic mini-cars game revisited
ScummVM
Play classic graphical adventure games on Mac
Simutrans
Build your own transport company and make it profitable
Snes9X
SNES emulator that letsyou record play as QT movies